منابع مشابه
A clinical comparison of sodium thiopental (pentothal), sodium methitural (neraval), sodium buthalitone (transithal), and sodium hexobarbital (evipal).
Much ~ been written m recent years of the relative advantages and chsadvantages of new intravenous anaesthetics. Such comparisons are always difficult to make because of the many variables which ca~Lnot be easily controlled in a clinical series. For that reason, we attempted some time ago to compare a number of intravenous agents in human vol~mteers, a&a~inistering each drug consecutively to th...
متن کاملThe comparative potencies of buthalitone and thiopentone in out-patient anaesthesia.
THIOPENTONE was introduced to clinical anaesthesia by Lundy in 1934 and the first reports of its use appeared in the following year (Lundy, 1935; Lundy and Tovell, 1935). Since then, thiopentone has almost entirely superseded other intravenous agents and has become the standard agent for inducing anaesthesia. It is not, however, without certain dangers. The main disadvantages are the occasional...
متن کاملFurther experiences with methylated thiobarbiturates.
FIG. 1 Formulae of the drug under study. Limited supplies of two further methylated thiobarbiturates, described by Peel et al. (1959), known as B.82 and B.133 have become available. The formulae of these are shown in figure 1 and it can be seen that B.82 is the methylated form of buthalitone. B.133 is not related chemically to any thiobarbiturate in clinical use, being sodium N-methyl 5-ethyl 5...
متن کاملClinical studies of induction agents. XVI: a comparison of thiopentone, buthalitone, hexobarbitone and thiamylal as induction agents.
Results are presented of a comparative clinical trial of thiopentone, buthalitone, hexobarbitone and thiamylal, which extended over five years and was carried out by twenty-three anaesthetists. Thiopentone and thiamylal produced consistently good anaesthesia, but the respiratory and circulatory complications occurring with hexobarbitone and buthalitone were of sufficient frequency and severity ...
متن کاملSodium Channel and Sodium
Levels of sodium pump and of sodium channels were measured at different stages of membrane purification. Microsomal fractions of normal human muscle have maximal binding capacities for tetrodotoxin of 230 fmol/mg of protein and of 7.4 pmol/mg of protein for ouabain. Dissociation constant for the complexes formed by the tetrodotoxin derivative and by ouabain with their respective receptors were ...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1959
ISSN: 0007-0912
DOI: 10.1093/bja/31.12.533